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  4. Self-supervised Learning of Inter-label Geometric Relationships for Gleason Grade Segmentation
 
conference paper

Self-supervised Learning of Inter-label Geometric Relationships for Gleason Grade Segmentation

Mahapatra, Dwarikanath
•
Kuanar, Shiba
•
Bozorgtabar, Behzad  
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January 1, 2021
Domain Adaptation And Representation Transfer, And Affordable Healthcare And Ai For Resource Diverse Global Health (Dart 2021)
3rd MICCAI Workshop on Domain Adaptation and Representation Transfer (DART)

Segmentation of Prostate Cancer (PCa) tissues from Gleason graded histopathology images is vital for accurate diagnosis. Although deep learning (DL) based segmentation methods achieve state-of-the-art accuracy, they rely on large datasets with manual annotations. We propose a method to synthesize PCa histopathology images by learning the geometrical relationship between different disease labels using self-supervised learning. Manual segmentation maps from the training set are used to train a Shape Restoration Network (ShaRe-Net) that predicts missing mask segments in a self-supervised manner. Using DenseUNet as the backbone generator architecture we incorporate latent variable sampling to inject diversity in the image generation process and thus improve robustness. Experimental results demonstrate the superiority of our method over competing image synthesis methods for segmentation tasks. Ablation studies show the benefits of integrating geometry and diversity in generating high-quality images. Our self-supervised approach with limited class-labeled data achieves better performance than fully supervised learning.

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Type
conference paper
DOI
10.1007/978-3-030-87722-4_6
Web of Science ID

WOS:000722283000006

Author(s)
Mahapatra, Dwarikanath
Kuanar, Shiba
Bozorgtabar, Behzad  
Ge, Zongyuan
Date Issued

2021-01-01

Publisher

Springer International Publishing

Publisher place

Cham

Published in
Domain Adaptation And Representation Transfer, And Affordable Healthcare And Ai For Resource Diverse Global Health (Dart 2021)
ISBN of the book

978-3-030-87722-4

978-3-030-87721-7

Series title/Series vol.

Lecture Notes in Computer Science

Volume

12968

Start page

57

End page

67

Subjects

Computer Science, Interdisciplinary Applications

•

Mathematical & Computational Biology

•

Computer Science

•

self-supervised learning

•

geometric modeling

•

gans

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LTS5  
Event nameEvent placeEvent date
3rd MICCAI Workshop on Domain Adaptation and Representation Transfer (DART)

Strasbourg, France

Sep 27-Oct 01, 2021

Available on Infoscience
December 18, 2021
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/183928
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