In order to take advantage of the massive parallelism offered by artificial neural networks, hardware implementations are essential.However, most standard neural network models are not very suitable for implementation in hardware and adaptations are needed. In this section an overview is given of the various issues that are encountered when mapping an ideal neural network model onto a compact and reliable neural network hardware implementation, like quantization, handling nonuniformities and nonideal responses, and restraining computational complexity. Furthermore, a broad range of hardware-friendly learning rules is presented, which allow for simpler and more reliable hardware implementations. The relevance of these neural network adaptations to hardware is illustrated by their application in existing hardware implementations.