Recently, a technique called beam-space MIMO has been demonstrated as an effective approach for transmitting multiple signals while using a single RF-chain. In this work, we present novel design considerations and a compact antenna solution to stimulate the deployment of beam-space MIMO in future wireless applications. Targeting integration in small wireless devices, the novel antenna is made of a single integrated radiator rather than an array of physically-separated dipoles. It also drastically simplifies the implementation of variable loads and DC bias circuits for BPSK modulated signals, and does not require any external reconfigurable matching circuit. Finally, we show that this antenna system could be reconfigured by dynamic adjustment of terminating loads to preserve its beam-space multiplexing capabilities over a 1:2 tuning range, thereby promoting the convergence of MIMO and dynamic spectrum allocation via reduced-complexity hardware. A prototype achieving single-RF-chain multiplexing at a fixed frequency is designed and measured, showing excellent agreement between simulations and measurements.