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research article

Assessment of distributed arterial network models

Segers, P
•
Stergiopulos, N  
•
Verdonck, P
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1998
Medical & biological engineering & computing

The aim of this study is to evaluate the relative importance of elastic non-linearities, viscoelasticity and resistance vessel modelling on arterial pressure and flow wave contours computed with distributed arterial network models. The computational results of a non-linear (time-domain) and a linear (frequency-domain) mode were compared using the same geometrical configuration and identical upstream and downstream boundary conditions and mechanical properties. pressures were computed at the ascending aorta, brachial and femoral artery. In spite of the identical problem definition, computational differences were found in input impedance modulus (max. 15-20%), systolic pressure (max. 5%) and pulse pressure (max. 10%). For the brachial artery, the ratio of pulse pressure to aortic pulse pressure was practically identical for both models (3%), whereas for the femoral artery higher values are found for the linear model (+10%). The aortic/brachial pressure transfer function indicates that pressure harmonic amplification is somewhat higher in the linear model for frequencies lower than 6 Hz while the opposite is true for higher frequencies. These computational disparities were attributed to conceptual model differences, such as the treatment of geometric tapering, rather than to elastic or convective non-linearities. Compared to the effect of viscoelasticity, the discrepancy between the linear and non-linear model is of the same importance. At peripheral locations, the correct representation of terminal impedance outweight the computational differences between the linear and non-linear models.

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Type
research article
DOI
10.1007/BF02510985
PubMed ID

9538553

Author(s)
Segers, P
Stergiopulos, N  
Verdonck, P
Verhoeven, R
Date Issued

1998

Published in
Medical & biological engineering & computing
Volume

35

Issue

6

Start page

729

End page

36

Subjects

Models, Cardiovascular

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LHTC  
Available on Infoscience
December 16, 2010
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/62301
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