Computational approaches are breaking new ground in understanding how embryos form. Here, we discuss recent studies that couple precise measurements in the embryo with appropriately matched modeling and computational methods to investigate classic embryonic patterning strategies. We include signaling gradients, activator-inhibitor systems, and coupled oscillators, as well as emerging paradigms such as tissue deformation. Parallel progress in theory and experiment will play an increasingly central role in deciphering developmental patterning.
Type
research article
Scopus ID
2-s2.0-84859633304
Authors
Publication date
2012
Published in
Volume
336
Issue
6078
Start page
187
End page
191
Subjects
Peer reviewed
REVIEWED
Written at
OTHER
EPFL units
Available on Infoscience
May 30, 2017
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