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  4. Adaptation and Optimization of an Intraneural Electrode to Interface with the Cervical Vagus Nerve
 
conference paper

Adaptation and Optimization of an Intraneural Electrode to Interface with the Cervical Vagus Nerve

Strauss, Ivo
•
Zinno, Ciro
•
Giannotti, Alice
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January 1, 2021
2021 10Th International Ieee/Embs Conference On Neural Engineering (Ner)
10th International IEEE-EMBS Conference on Neural Engineering (NER)

The modulation of the cervical vagus nerve (VN) using neural electrodes has shown great potential to treat cardiovascular, inflammatory, intestinal, or respiratory dysfunctions. Intraneural electrodes have shown great potentials for other neuroprosthetic applications. Therefore, their use for VN modulation could have great potential. Here we optimized an intraneural electrode originally developed for use in lower limb amputees. Based on histological data from the VN of 100 histological sections we adapted and optimized the dimensions of the Quick-to-implant peripheral neural electrode (Q-PINE). Parts of the Q- PINE were substituted to increase biocompatibility. The platinum-iridium (Pt/Ir) wires were substituted with a polyimide thin-film structure to optimize the electrodes' impedance. Mechanical and electrochemical characterization was performed to exclude negative alterations resulting from the design and material changes. The dimensional adaptation and material substitutions of the Q- PINE did not alter its mechanical or electrochemical properties. The tfQPINE shows promising results for the successful application with the VN.

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Type
conference paper
DOI
10.1109/NER49283.2021.9441131
Web of Science ID

WOS:000681358200024

Author(s)
Strauss, Ivo
•
Zinno, Ciro
•
Giannotti, Alice
•
Ottaviani, Matteo M.
•
Recchia, Fabio A.
•
Micera, Silvestro  
Date Issued

2021-01-01

Publisher

IEEE

Publisher place

New York

Published in
2021 10Th International Ieee/Embs Conference On Neural Engineering (Ner)
ISBN of the book

978-1-7281-4337-8

Series title/Series vol.

International IEEE EMBS Conference on Neural Engineering

Start page

116

End page

119

Subjects

Computer Science, Theory & Methods

•

Engineering, Biomedical

•

Neurosciences

•

Computer Science

•

Engineering

•

Neurosciences & Neurology

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
TNE  
Event nameEvent placeEvent date
10th International IEEE-EMBS Conference on Neural Engineering (NER)

Prague, ELECTR NETWORK

May 04-06, 2021

Available on Infoscience
August 28, 2021
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/180887
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