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research article

TIBA: a tool for phylogeny inference from rearrangement data with bootstrap analysis

Lin, Yu  
•
Rajan, Vaibhav  
•
Moret, Bernard M. E.  
2012
Bioinformatics

TIBA is a tool to reconstruct phylogenetic trees from rearrangement data that consist of ordered lists of synteny blocks (or genes), where each synteny block is shared with all of its homologues in the input genomes. The evolution of these synteny blocks, through rearrangement operations, is modelled by the uniform Double-Cut-and-Join model. Using a true distance estimate under this model and simple distance-based methods, TIBA reconstructs a phylogeny of the input genomes. Unlike any previous tool for inferring phylogenies from rearrangement data, TIBA uses novel methods of robustness estimation to provide support values for the edges in the inferred tree.

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Type
research article
DOI
10.1093/bioinformatics/bts603
Web of Science ID

WOS:000312105300025

Author(s)
Lin, Yu  
Rajan, Vaibhav  
Moret, Bernard M. E.  
Date Issued

2012

Publisher

Oxford University Press

Published in
Bioinformatics
Volume

28

Issue

24

Start page

3324

End page

3325

Note

National Licences

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LCBB  
Available on Infoscience
March 28, 2013
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/91177
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