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research article

Prognosis of cancer survivors: estimation based on differential equations

Ryalen, Pal C.  
•
Moller, Bjorn
•
Laache, Christoffer H.
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September 24, 2021
Biostatistics

We present a method for estimating several prognosis parameters for cancer survivors. The method utilizes the fact that these parameters solve differential equations driven by cumulative hazards. By expressing the parameters as solutions to differential equations, we develop generic estimators that are easy to implement with standard statistical software. We explicitly describe the estimators for prognosis parameters that are often employed in practice, but also for parameters that, to our knowledge, have not been used to evaluate prognosis. We then apply these parameters to assess the prognosis of five common cancers in Norway.

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Type
research article
DOI
10.1093/biostatistics/kxab009
Web of Science ID

WOS:000756580000001

Author(s)
Ryalen, Pal C.  
Moller, Bjorn
Laache, Christoffer H.
Stensrud, Mats J.  
Roysland, Kjetil
Date Issued

2021-09-24

Published in
Biostatistics
Article Number

kxab009

Subjects

Mathematical & Computational Biology

•

Statistics & Probability

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Mathematical & Computational Biology

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Mathematics

•

cancer

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cancer survivors

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conditional survival

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prognosis

•

survival analysis

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
BIOSTAT  
Available on Infoscience
February 28, 2022
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/185824
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