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  4. Characterisation of the promoter for the LexA regulated sulA gene of Escherichia coli
 
research article

Characterisation of the promoter for the LexA regulated sulA gene of Escherichia coli

Cole, S T  
1983
Molecular & general genetics : MGG

The sulA gene of Escherichia coli, which encodes an inducible inhibitor of cell division, plays a role in the SOS response. Its expression, like that of other SOS genes, is repressed by the LexA protein. This paper reports the identification and characterisation of the promoter for the cloned sulA gene. The promoter bears good resemblance to the consensus promoter sequence and directs the synthesis of two major RNA species both in vitro and in vivo. Comparison of the sequence around the sulA promoter with the operator sequences of other SOS genes revealed the presence of an SOS box, the LexA protein binding site. This overlaps the -10 region of the promoter and covers the transcriptional initiation sites. LexA protein bound to this SOS box, would, therefore, effectively block transcription.

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Type
research article
DOI
10.1007/BF00325901
PubMed ID

6306396

Author(s)
Cole, S T  
Date Issued

1983

Published in
Molecular & general genetics : MGG
Volume

189

Issue

3

Start page

400

End page

4

Subjects

Gene Expression Regulation

•

Genes, Bacterial

•

Operon

•

Serine Endopeptidases

Editorial or Peer reviewed

REVIEWED

Written at

OTHER

EPFL units
UPCOL  
Available on Infoscience
September 7, 2010
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/53305
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