New fluorinated host compounds, namely, 2,4,6-tris(4-bromo-3-fluorophenoxy) -1,3,5-triazine, 2,4,6-tris(4-bromo-3,5-difluorophenoxy)-1,3,5-triazine, and 2,4,6-tris(4-bromo-2,6-difluorophenoxy)-1,3,5-triazine, were synthesized to investigate the effect of fluorine on the inclusion behavior. The altered electrostatic potential of the channel wall caused by fluorine substituents led to essential differences in host-guest interactions which were demonstrated by the inclusion of large guest molecules such as fullerenes, decamethylferrocene, or bucky-ferrocene. © 2007 American Chemical Society.