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research article
Mycobacterium tuberculosis: drug-resistance mechanisms
Tuberculosis has resurged during the past decade in many industrialized countries, and strains of Mycobacterium tuberculosis that are resistant to one or more of the main antituberculous drugs are emerging. The molecular basis of mycobacterial drug resistance is now beginning to be understood. Resistance derives from mutations in chromosomal genes leading to overproduction, alteration or loss of the drug target.
Type
research article
PubMed ID
7850211
Authors
Publication date
1994
Published in
Volume
2
Issue
10
Start page
411
End page
5
Peer reviewed
REVIEWED
Written at
OTHER
EPFL units
Available on Infoscience
September 7, 2010
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