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  4. EPISeg: Automated segmentation of the spinal cord on echo planar images using open-access multi-center data
 
preprint

EPISeg: Automated segmentation of the spinal cord on echo planar images using open-access multi-center data

Banerjee, Rohan
•
Kaptan, Merve
•
Tinnermann, Alexandra
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January 27, 2025

Functional magnetic resonance imaging (fMRI) of the spinal cord is relevant for studying sensation, movement, and autonomic function. Preprocessing of spinal cord fMRI data involves segmentation of the spinal cord on gradient-echo echo planar imaging (EPI) images. Current automated segmentation methods do not work well on these data, due to the low spatial resolution, susceptibility artifacts causing distortions and signal drop-out, ghosting, and motion-related artifacts. Consequently, this segmentation task demands a considerable amount of manual effort which takes time and is prone to user bias. In this work, we (i) gathered a multi-center dataset of spinal cord gradient-echo EPI with ground-truth segmentations and shared it on OpenNeuro https://openneuro.org/datasets/ds005143/versions/1.3.0 , and (ii) developed a deep learning-based model, EPISeg, for the automatic segmentation of the spinal cord on gradient-echo EPI data. We observe a significant improvement in terms of segmentation quality compared to other available spinal cord segmentation models. Our model is resilient to different acquisition protocols as well as commonly observed artifacts in fMRI data. The training code is available at https://github.com/sct-pipeline/fmri-segmentation/ , and the model has been integrated into the Spinal Cord Toolbox as a command-line tool.

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Type
preprint
DOI
10.1101/2025.01.07.631402
Author(s)
Banerjee, Rohan

Mila - Quebec Artificial Intelligence Institute

Kaptan, Merve

Stanford University

Tinnermann, Alexandra

University Medical Center Hamburg-Eppendorf

Khatibi, Ali

University of Birmingham

Dabbagh, Alice

Max Planck Institute for Human Cognitive and Brain Sciences

Kündig, Christian W.

Universitätsklinik Balgrist

Law, Christine S.

Stanford University

Pfyffer, Dario

Stanford University

Lythgoe, David J.

King's College London

Tsivaka, Dimitra

University of Thessaly

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Date Issued

2025-01-27

Publisher

bioRxiv

Subjects

Spinal Cord

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Echo Planar Imaging

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Functional Magnetic Resonance Imaging

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Segmentation

Written at

EPFL

EPFL units
MIPLAB  
Available on Infoscience
May 27, 2025
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/250800
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