Over the years, multimodal mobile sensing has been used extensively for inferences regarding health and well-being, behavior, and context. However, a significant challenge hindering the widespread deployment of such models in real-world scenarios is the issue of distribution shift. This is the phenomenon where the distribution of data in the training set differs from the distribution of data in the real world-the deployment environment. While extensively explored in computer vision and natural language processing, and while prior research in mobile sensing briefly addresses this concern, current work primarily focuses on models dealing with a single modality of data, such as audio or accelerometer readings, and consequently, there is little research on unsupervised domain adaptation when dealing with multimodal sensor data. To address this gap, we did extensive experiments with domain adversarial neural networks (DANN) showing that they can effectively handle distribution shifts in multimodal sensor data. Moreover, we proposed a novel improvement over DANN, called M3BAT, unsupervised domain adaptation formultimodalmobile sensing withmulti-branch adversarial training, to account for the multimodality of sensor data during domain adaptation with multiple branches. Through extensive experiments conducted on two multimodal mobile sensing datasets, three inference tasks, and 14 source-target domain pairs, including both regression and classification, we demonstrate that our approach performs effectively on unseen domains. Compared to directly deploying a model trained in the source domain to the target domain, the model shows performance increases up to 12% AUC (area under the receiver operating characteristics curves) on classification tasks, and up to 0.13 MAE (mean absolute error) on regression tasks.