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The worm that died in a blaze of blue glory

Henry, Luc  
July 26, 2013

Never has "feeling blue" carried such a sense of finality. A new study has revealed the simple worm (Caenorhabditis elegans) meets its death in a flash of azure. And, according to researchers, the blue light shows that dying may be a coordinated process that could probably be delayed. Scientists have known for many years that cells can die in two ways. Necrosis occurs when either the cell's machinery breaks down with age, or exposure to trauma damages the cell beyond repair. Apoptosis is a programmed process triggered on demand, by which even healthy cells can undergo a series of changes resulting in an orderly death. But when it comes to multicellular organisms dying, such as humans, defining the exact mechanisms becomes more complicated. It cannot simply be explained by a bunch of cells dying independently. How do you define the precise moment when an animal stops being alive and what is the sequence of events leading to death? C. Elegans alive (left) and dead (right). Wellcome Trust 

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