research article
SERINE DERIVED OXAZOLIDINES AS SECONDARY STRUCTURE DISRUPTING, SOLUBILIZING BUILDING-BLOCKS IN PEPTIDE-SYNTHESIS
1992
The incorporation of serine as oxazolidine protected ''pseudo proline'' in a host peptide results in the disruption of secondary structure formation thus increasing the solvation of the peptide chain. The use of this protection technique for serine, threonine or cysteine represents a powerful tool to modulate the conformational and physico- chemical properties of peptides.
Type
research article
Author(s)
HAACK, T
Date Issued
1992
Publisher
Published in
Volume
33
Issue
12
Start page
1589
End page
1592
Editorial or Peer reviewed
REVIEWED
Written at
EPFL
EPFL units
Available on Infoscience
February 9, 2006
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