Loading...
review article
Tumor-suppressor gene products in cell contacts: the cadherin-APC-armadillo connection
Various structural components of intercellular junctions have recently been found to represent (or be related to) products of tumor-suppressor genes. The tumor-suppressor gene product adenomatous polyposis coli (APC) binds to beta 2-catenin (homologous to the product of Drosophila armadillo), which is cytoplasmically associated with the cell adhesion molecule E-cadherin
Type
review article
Authors
Publication date
1994
Published in
Volume
6
Issue
5
Start page
711
End page
716
Note
Author address: Max-Delbruck-Center for Molecular Medicine, Berlin, Germany
Peer reviewed
REVIEWED
Written at
OTHER
EPFL units
Available on Infoscience
February 13, 2008
Use this identifier to reference this record