Repository logo

Infoscience

  • English
  • French
Log In
Logo EPFL, École polytechnique fédérale de Lausanne

Infoscience

  • English
  • French
Log In
  1. Home
  2. Academic and Research Output
  3. Journal articles
  4. Integration of activation maps of epicardial veins in computational cardiac electrophysiology
 
research article

Integration of activation maps of epicardial veins in computational cardiac electrophysiology

Stella, Simone
•
Vergara, Christian
•
Maines, Massimiliano
Show more
December 1, 2020
Computers In Biology And Medicine

In this work we address the issue of validating the monodomain equation used in combination with the Bueno-Orovio ionic model for the prediction of the activation times in cardiac electro-physiology of the left ventricle. To this aim, we consider four patients who suffered from Left Bundle Branch Block (LBBB). We use activation maps performed at the septum as input data for the model and maps at the epicardial veins for the validation. In particular, a first set (half) of the latter are used to estimate the conductivities of the patient and a second set (the remaining half) to compute the errors of the numerical simulations. We find an excellent agreement between measures and numerical results. Our validated computational tool could be used to accurately predict activation times at the epicardial veins with a short mapping, i.e. by using only a part (the most proximal) of the standard acquisition points, thus reducing the invasive procedure and exposure to radiation.

  • Details
  • Metrics
Type
research article
DOI
10.1016/j.compbiomed.2020.104047
Web of Science ID

WOS:000605607900001

Author(s)
Stella, Simone
Vergara, Christian
Maines, Massimiliano
Catanzariti, Domenico
Africa, Pasquale Claudio
Dematte, Cristina
Centonze, Maurizio
Nobile, Fabio  
Del Greco, Maurizio
Quarteroni, Alfio  
Date Issued

2020-12-01

Publisher

PERGAMON-ELSEVIER SCIENCE LTD

Published in
Computers In Biology And Medicine
Volume

127

Article Number

104047

Subjects

Biology

•

Computer Science, Interdisciplinary Applications

•

Engineering, Biomedical

•

Mathematical & Computational Biology

•

Life Sciences & Biomedicine - Other Topics

•

Computer Science

•

Engineering

•

cardiac electro-physiology

•

monodomain equation

•

bueno-orovio ionic model

•

activation times

•

ensite precision system

•

cardiac resynchronization therapy

•

ventricular action-potentials

•

purkinje network driven

•

clinical measurements

•

conduction-velocity

•

fiber architecture

•

diffusion models

•

lead placement

•

heart

•

bidomain

•

tissue

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
CSQI  
Available on Infoscience
March 26, 2021
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/176546
Logo EPFL, École polytechnique fédérale de Lausanne
  • Contact
  • infoscience@epfl.ch

  • Follow us on Facebook
  • Follow us on Instagram
  • Follow us on LinkedIn
  • Follow us on X
  • Follow us on Youtube
AccessibilityLegal noticePrivacy policyCookie settingsEnd User AgreementGet helpFeedback

Infoscience is a service managed and provided by the Library and IT Services of EPFL. © EPFL, tous droits réservés