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  4. Cross-Coupling of Nonactivated Primary and Secondary Alkyl Halides with Aryl Grignard Reagents Catalyzed by Chiral Iron Pincer Complexes
 
research article

Cross-Coupling of Nonactivated Primary and Secondary Alkyl Halides with Aryl Grignard Reagents Catalyzed by Chiral Iron Pincer Complexes

Bauer, Gerald  
•
Cheung, Chi Wai  
•
Hu, Xile  
2015
Synthesis: Journal of Synthetic Organic Chemistry

Iron(III) bisoxazolinylphenylamido (bopa) pincer complexes are efficient precatalysts for the cross-coupling of nonactivated primary and secondary alkyl halides with phenyl Grignard reagents. The reactions proceed at room temperature in moderate to excellent yields. A variety of functional groups can be tolerated. The enantioselectivity of the coupling of secondary alkyl halides is low.

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Type
research article
DOI
10.1055/s-0034-1380136
Web of Science ID

WOS:000355700000006

Author(s)
Bauer, Gerald  
Cheung, Chi Wai  
Hu, Xile  
Date Issued

2015

Publisher

Georg Thieme Verlag

Published in
Synthesis: Journal of Synthetic Organic Chemistry
Volume

47

Issue

12

Start page

1726

End page

1732

Subjects

Kumada coupling

•

iron pincer complex

•

alkyl halide

•

aryl Grignard reagent

•

enantioselectivity

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LSCI  
Available on Infoscience
September 28, 2015
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/119340
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