A large-scale low-cost access to the lithium 2,2,6,6-tetramethylpiperidide precursor
Wolff-Kishner-Huang redn. of the cheap 2,2,6,6-tetramethyl-4-piperidinone provides the expensive 2,2,6,6-tetramethylpiperidine, the precursor to lithium 2,2,6,6-tetramethylpiperidide, in high yield. As specified in the detailed protocol, the reaction can be conveniently carried out on a >10 mol lab. scale. [on SciFinder (R)]
WOS:000228616300023
2005
6
1028
1029
CAN 142:392262
27-16
Heterocyclic Compounds (One Hetero Atom)
Gersthofen,Germany.
Journal
written in English.
826-36-8 (2,2,6,6-Tetramethyl-4-piperidinone) Role: RCT (Reactant), RACT (Reactant or reagent) (prepn. of 2,2,6,6-tetramethylpiperidine by Wolff-Kishner-Huang redn. of 2,2,6,6-tetramethyl-4-piperidinone); 768-66-1P (2,2,6,6-Tetramethylpiperidine) Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of 2,2,6,6-tetramethylpiperidine by Wolff-Kishner-Huang redn. of 2,2,6,6-tetramethyl-4-piperidinone)
REVIEWED
EPFL