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  4. Practical and Scalable Synthesis of 7-Azetidin-1-yl-4-(hydroxymethyl)coumarin: An Improved Photoremovable Group
 
research article

Practical and Scalable Synthesis of 7-Azetidin-1-yl-4-(hydroxymethyl)coumarin: An Improved Photoremovable Group

Bassolino, Giovanni
•
Halabi, Elias A.
•
Rivera-Fuentes, Pablo
2018
Synthesis: Journal of Synthetic Organic Chemistry

A robust and scalable route to prep. the 7-azetidinylated alc., a useful precursor for the photoprotection of a variety of leaving groups, and its use in the prepn. of model phosphate, sulfonate, and carbamate derivs. is presented.

  • Details
  • Metrics
Type
research article
DOI
10.1055/s-0036-1591742
Author(s)
Bassolino, Giovanni
Halabi, Elias A.
Rivera-Fuentes, Pablo
Date Issued

2018

Publisher

Georg Thieme Verlag

Published in
Synthesis: Journal of Synthetic Organic Chemistry
Volume

50

Start page

846

End page

852

Subjects

7 azetidin 1 yl 4 (hydroxymethyl)coumarin

•

7 azetidinylated alcohol

•

alcohol derivative

•

Article

•

azetidine

•

Azetidines

•

azetidinyl hydroxymethyl coumarin prepn

•

Biochemistry

•

bioorganic chemistry

•

Bioorganic chemistry

•

Buchwald Hartwig reaction

•

Carbamate derivatives

•

carbamic acid derivative

•

chemical reaction

•

chemical structure

•

chromophores

•

Chromophores

•

controlled study

•

coumarin derivative

•

phosphate

•

phosphate derivative

•

photoactivation

•

Photochemical reactions

•

photochemistry

•

Photoprotecting groups

•

photoprotection

•

Photoprotection

•

Protecting group

•

protecting groups

•

Scalable synthesis

•

Solutions

•

sulfonic acid derivative

•

synthesis

•

uncaging

•

unclassified drug

Editorial or Peer reviewed

REVIEWED

Written at

OTHER

EPFL units
LOCBP  
Available on Infoscience
October 30, 2019
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/162478
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