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review article

Regulatory Components for Bacterial Cell-Free Systems Engineering

Lee, Pao-Wan
•
Maerkl, Sebastian J.  
November 7, 2024
ACS Synthetic Biology

Cell-free systems are advancing synthetic biology through fast prototyping and modularity. Complex regulatory networks can now be implemented in cell-free systems enabling various applications, such as diagnostic tool development, gene circuit prototyping, and metabolic engineering. As functional complexity increases, the need for regulatory components also grows. This review provides a comprehensive overview of native as well as engineered regulatory components and their use in bacterial cell-free systems.

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Type
review article
DOI
10.1021/acssynbio.4c00574
Web of Science ID

WOS:001350026800001

PubMed ID

39509282

Author(s)
Lee, Pao-Wan
•
Maerkl, Sebastian J.  
Date Issued

2024-11-07

Publisher

AMER CHEMICAL SOC

Published in
ACS Synthetic Biology
Volume

13

Issue

12

Subjects

Synthetic biology

•

Gene regulatory network

•

Cell-free Systems

•

Gene circuits

Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LBNC  
FunderFunding(s)Grant NumberGrant URL

Schweizerischer Nationalfonds zur Frderung der Wissenschaftlichen Forschung

514558

Swiss National Science Foundation (SNSF)

514337

Swiss National Science Foundation MINT grant

Available on Infoscience
January 28, 2025
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/245666
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