This paper examines how demographic characteristics, institutional structures, and livelihood strategies shape household resilience to climate variability and drought in West Pokot County, one of Kenya's most climate-vulnerable arid and semi-arid lands (ASALs). Using a mixed-methods approach, it combines household survey data with three statistical techniques: Multinomial Logistic Regression (MLR) assesses the influence of gender, age, and education on livestock ownership and livelihood choices; Multiple Correspondence Analysis (MCA) reveals patterns in institutional access and adaptive practices; and Stepwise Linear Regression (SLR) quantifies the relationship between resilience strategies and agricultural productivity. Findings show that demographic factors, particularly gender and education, along with access to veterinary services, drought-tolerant inputs, and community-based organizations, significantly shape resilience. However, trade-offs exist: strategies improving livestock productivity may reduce crop yields due to resource and labor competition. This study recommends targeted interventions, including genderresponsive extension services, integration of indigenous and scientific knowledge, improved infrastructure, and participatory governance. These measures are vital for strengthening resilience not only in West Pokot but also in other drought-prone ASAL regions across sub-Saharan Africa.