A symposium report. A novel chem. approach for the synthesis of biotinylated glycosulfopeptides uses two different chemoselective ligation reactions in the presence of the sulfate moiety. The strategy was applied to the synthesis of a peptide sequence derived from the N-terminal region of the P-selectin glycoprotein ligand 1 (PSGL-1), a major ligand of the selectin family involved in cell-cell adhesion. [on SciFinder (R)]