The computational complexity of disparity estimation algorithms and the need of large size and bandwidth for the external and internal memory make the real-time processing of disparity estimation challenging, especially for High Resolution (HR) images. This paper proposes a hardware-oriented adaptive window size disparity estimation (AWDE) algorithm and its real time reconfigurable hardware implementation that targets HR video with high quality disparity results. The proposed algorithm is a hybrid solution involving the Sum of Absolute Differences and the Census cost computation methods to vote and select the best suitable disparity candidates. It utilizes a pixel intensity based refinement step to remove faulty disparity computations. The AWDE algorithm dynamically adapts the window size considering the local texture of the image to increase the disparity estimation quality. The proposed reconfigurable hardware of the AWDE algorithm enables handling 60 frames per second on Virtex-5 FPGA at a 1024×768 XGA video resolution for a 120 pixel disparity range.