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  4. Uniform broadband excitation of crystallites in rotating solids using interleaved sequences of delays alternating with nutation
 
research article

Uniform broadband excitation of crystallites in rotating solids using interleaved sequences of delays alternating with nutation

Vitzthum, Veronika  
•
Caporini, Marc A.  
•
Ulzega, Simone  
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2012
Journal of Magnetic Resonance

In solids that are spinning about the magic angle, trains of short pulses in the manner of Delays Alternating with Nutations for Tailored Excitation (DANTE) allow one to improve the efficiency of the excitation of magnetization compared to rectangular pulses. By interleaving N pulse trains with N > 1, one obtains 'DANTE-N' sequences comprising N pulses per rotor period that extend over K rotor periods. Optimized interleaved DANTE schemes with N > 1 are shorter than basic DANTE-1 sequences with N = 1. Therefore, they are less affected by coherent or incoherent decays, thus leading to higher signal intensities than can be obtained with basic DANTE-1 or with rectangular pulses. Furthermore, the shorter length of DANTE-N with N > 1 increases the width of the spikelets in the excitation profile, allowing one to cover the range of isotropic chemical shifts and second-order quadrupolar effects typical for side-chain and backbone amide N-14 sites in peptides at B-0 = 18.8 T. In DANTE-N, spinning sidebands only appear at multiples of the spinning frequency nu(rot), as if the samples were rotating at N nu(rot). We show applications to direct detection of nitrogen-14 nuclei with spin I = 1 subject to large quadrupole interactions, using fast magic angle spinning (typically nu(rot) >= 60 kHz), backed up by simulations that provide insight into the properties of basic and interleaved DANTE sequences. When used for indirect detection, we show by numerical simulations that even basic DANTE-1 sequences can lead to a four-fold boost of efficiency compared to standard rectangular pulses. (C) 2012 Elsevier Inc. All rights reserved.

  • Details
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Type
research article
DOI
10.1016/j.jmr.2012.05.024
Web of Science ID

WOS:000309570600031

Author(s)
Vitzthum, Veronika  
Caporini, Marc A.  
Ulzega, Simone  
Trébosc, Julien
Lafon, Olivier
Amoureux, Jean-Paul
Bodenhausen, Geoffrey  
Date Issued

2012

Publisher

Academic Press Inc - Elsevier Science

Published in
Journal of Magnetic Resonance
Volume

223

Start page

228

End page

236

Subjects

Nitrogen-14 NMR

•

Delays Alternating with Nutations for Tailored Excitation (DANTE)

•

Interleaved DANTE

•

Dipolar Heteronuclear Multiple-Quantum Correlation (D-HMQC)

•

Solid-state NMR

•

Magic Angle Spinning (MAS)

•

Broadband excitation

•

Quadrupolar nuclei

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LRMB  
Available on Infoscience
September 26, 2012
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/85704
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