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  4. Implementation of an Electrostatic Device for Investigation of Electric Fields on Cells
 
semester or other student projects

Implementation of an Electrostatic Device for Investigation of Electric Fields on Cells

Aziz, Alain Aziz Kamal  
June 7, 2024

Dielectric Elastomer Actuators (DEAs) have a wide range of applications. They can be widely used in research to study cells under mechanical movement or stress. This is done by culturing the cells in vitro on the DEA and observing, under the microscope, the morphological and the numerous other important changes they are experiencing. However, in order to make sure that the effects observed on the cells are in fact from the mechanical stimuli alone, no other factors should be influencing the cells. Therefore we want to study the effects of other physical phenomenons on the cells, most importantly electric fields. Electric fields are known to have many different effects on cells. Since typically a voltage of 6 kV is applied on the electrodes of a DEA, there might be significant leakages that can affect or even kill the cells. In this project a DEA is modified in order to study the effects of electric field leakages on cells without the mechanical stimulation. To do so, the elastic dielectric material of the DEA is replaced with alternative rigid materials like Kapton or Polyethylene terephthalate (PET). Simulations are conducted to test the devices' electrical and mechanical properties. The devices are then fabricated and characterised. This report will allow further studies on cells using DEAs, potentially facilitating their use in the medical field.

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Type
semester or other student projects
Author(s)
Aziz, Alain Aziz Kamal  

EPFL

Advisors
Holzer, Simon  
•
Perriard, Yves  
Date Issued

2024-06-07

Publisher

EPFL

Publisher place

Lausanne

Total of pages

19

Written at

EPFL

EPFL units
LAI  
CAM  
Faculty
STI  
Section
MT-S  
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/241023
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