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research article

Sufficient Cause Interaction for Time-to-event Outcomes

Stensrud, Mats Julius  
•
Ryalen, Pål Christie
•
Røysland, Kjetil
March 1, 2019
Epidemiology

Methods to assess sufficient cause interactions are well developed for binary outcomes. We extend these methods to handle time-to-event outcomes, which occur frequently in medicine and epidemiology. Based on theory for marginal structural models in continuous time, we show how to assess sufficient cause interaction nonparametrically, allowing for censoring and competing risks. We apply the method to study interaction between intensive blood pressure therapy and statin treatment on all-cause mortality.

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Type
research article
DOI
10.1097/EDE.0000000000000958
Author(s)
Stensrud, Mats Julius  
•
Ryalen, Pål Christie
•
Røysland, Kjetil
Date Issued

2019-03-01

Published in
Epidemiology
Volume

30

Issue

2

Start page

189

End page

196

Peer reviewed

REVIEWED

Written at

OTHER

EPFL units
BIOSTAT  
Available on Infoscience
October 15, 2020
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/172549
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