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research article
A Linear Approach to Multi-Panel Sensing in Personalized Therapy for Cancer Treatment
2013
In this paper, a new approach for evaluating the performance of a multi-panel biosensor using linear algebra is presented. With a system-level mathematical analysis based on graphs and linear algebra, we formulate a new approach for contributions decoupling in a multi-panel biochip for simulta- neous detection of anti-cancer drugs, avoiding redundancy and interaction between enzymes. Experimental results have been used to validate the model.
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