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  4. Pi-Allyl Palladium Methodology for Selective Deprotection of Allylamines. Practical Synthesis of Secondary Amines
 
research article

Pi-Allyl Palladium Methodology for Selective Deprotection of Allylamines. Practical Synthesis of Secondary Amines

Lemaire-Audoire, Sandrine
•
Savignac, Monique
•
Dupuis, Christophe
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1995
Bulletin de la société chimique de France

The palladium-promoted deallylation of allylamines derived from primary and secondary amines is achieved with high to quantitative yield in the presence of 2-mercaptobenzoic acid as an allyl scavenger. This method was used for the sequential cleavage of diallylamines. A. synthetic application of this procedure is presented in the preparation of secondary amines from diallylamines.

  • Details
  • Metrics
Type
research article
Author(s)
Lemaire-Audoire, Sandrine
Savignac, Monique
Dupuis, Christophe
Genêt, Jean-Pierre
Date Issued

1995

Published in
Bulletin de la société chimique de France
Volume

132

Issue

11

Start page

1157

End page

1166

Subjects

allyloxycarbonyl protecting group

•

alpha-aminophosphonic acids

•

lithiumamide bases

•

asymmetric-synthesis

•

hexamethylphosphoramide hmpa

•

catalyzed reactions

•

michael additions

•

aromatic-amines

•

schiff-bases

•

alkylation

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LGSA  
Available on Infoscience
June 16, 2006
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/231896
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