Generation of Human iPSC-Derived Neurons on Nanowire Arrays Human induced pluripotent stem cells (iPSCs) are used to generate functional neurons while being cultured on nanowire arrays. The variation of the substrate geometries such as nanowire length and array pitch elicits varying settling regimes and causes changing degrees of interaction with the cell's nucleus as reported by Jann Harberts, Robert Zierold, and co-workers in article number 2200806.