The equivalence of Boolean functions with respect to five invariance (aka translation) operations has been well considered with respect to the Rademacher-Walsh spectral domain. In this paper, we introduce a hybrid approach that uses both the Reed-Muller and the Rademacher-Walsh spectra. A novel hybrid algorithm that maps a Boolean function to a representative function for the equivalence class containing the original function is presented. The algorithm can be used to determine a sequence of translations that maps one function to an equivalent function. We present experimental results that show the hybrid algorithm can determine the equivalence classes for 5 variables much more efficiently than before. We also show that for 6 variables where there are 150,357 equivalence classes, 8 are very difficult, a further 58 are difficult and the remainder are straightforward in terms of the CPU time required by the hybrid algorithm.