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book part or chapter

Encapsulated cell implants as a novel treatment for Parkinson’s disease

Tseng, J.
•
Aebischer, P  
Mouradian, M. M.
2001
Parkinson's disease: Methods and Protocols

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the progressive degeneration of the dopaminergic cells of the substantia nigra pars compacta (SNPc). Systemic levodopa therapy has proved to be an effective initial treatment for this disorder. However, resistance to this therapy inevitably develops with time, necessitating other approaches including surgery. Current experimental surgical treatments for this disorder include pallidal stimulation, pallidal lesion, subthalamic stimulation, and dopaminergic cell transplants. The current limitation of these approaches is that they all treat the symptoms but not the cause, that is, the progressive degeneration of the SNPc goes unabated

  • Details
  • Metrics
Type
book part or chapter
Author(s)
Tseng, J.
Aebischer, P  
Editors
Mouradian, M. M.
Date Issued

2001

Publisher

Humana Press

Publisher place

Totowa, NJ

Published in
Parkinson's disease: Methods and Protocols
Start page

279

End page

288

Series title/Series vol.

Methods in Molecular Medicine; 62

Written at

OTHER

EPFL units
LEN  
Available on Infoscience
September 10, 2008
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/27838
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