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  4. Facilitating skilled right hand motor function in older subjects by anodal polarization over the left primary motor cortex
 
research article

Facilitating skilled right hand motor function in older subjects by anodal polarization over the left primary motor cortex

Hummel, Friedhelm C
•
Heise, Kirstin
•
Celnik, Pablo
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2010
Neurobiology of aging

Healthy ageing is accompanied by limitations in performance of activities of daily living and personal independence. Recent reports demonstrated improvements in motor function induced by noninvasive anodal direct current stimulation (tDCS) of the primary motor cortex (M1) in young healthy adults. Here we tested the hypothesis that a single session of anodal tDCS over left M1 could facilitate performance of right upper extremity tasks required for activities of daily living (Jebsen-Taylor hand function test, JTT) in older subjects relative to Sham in a double-blind cross-over study design. We found (a) significant improvement in JTT function with tDCS relative to Sham that outlasted the stimulation period by at least 30 min, (b) that the older the subjects the more prominent this improvement appeared and (c) that consistent with previous results in younger subjects, these effects were not accompanied by any overt undesired side effect. We conclude that anodal tDCS applied over M1 can facilitate performance of skilled hand functions required for activities of daily living in older subjects.

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Type
research article
DOI
10.1016/j.neurobiolaging.2008.12.008
Author(s)
Hummel, Friedhelm C
Heise, Kirstin
Celnik, Pablo
Floel, Agnes
Gerloff, Christian
Cohen, Leonardo G
Date Issued

2010

Publisher

Elsevier

Published in
Neurobiology of aging
Volume

31

Issue

12

Start page

2160

End page

8

Editorial or Peer reviewed

REVIEWED

Written at

OTHER

EPFL units
UPHUMMEL  
Available on Infoscience
December 29, 2016
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/132341
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