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research article

Total Synthesis of Cyrneine A

Elamparuthi, Elangovan
•
Fellay, Cindy
•
Neuburger, Markus
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2012
Angewandte Chemie International Edition

The tricyclic diterpene cyrneine A featuring a hexatrienal unit was prepared synthetically for the first time by a Heck reaction, a carbene ring expansion, and a reductive carbonylation. The structure of the natural product was assigned by X‐ray crystal analysis of a synthetic sample.

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Type
research article
DOI
10.1002/anie.201200515
Web of Science ID

WOS:000303001000012

Author(s)
Elamparuthi, Elangovan
Fellay, Cindy
Neuburger, Markus
Gademann, Karl  
Date Issued

2012

Publisher

Wiley-VCH Verlag GmbH

Published in
Angewandte Chemie International Edition
Volume

51

Start page

4071

End page

4073

Subjects

cross-coupling

•

natural products

•

neurochemistry

•

stereoselective synthesis

•

total synthesis

•

Ring Enlargement Reaction

•

Asymmetric-Synthesis

•

Tricyclic Core

•

Cyathin Diterpenoids

•

Heck Reaction

•

Intermediate

•

Cyclization

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LSYNC  
Available on Infoscience
May 18, 2012
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/80597
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