conference paper
Impact of MCT1 Haploinsufficiency on the Mouse Retina
January 1, 2018
Retinal Degenerative Diseases: Mechanisms And Experimental Therapy
The monocarboxylate transporter 1 (MCT1) is highly expressed in the outer retina, suggesting that it plays a critical role in photoreceptors. We examined MCT1+/- heterozygotes, which express half of the normal complement of MCT1. The MCT1(+/-) retina developed normally and retained normal function, indicating that MCT1 is expressed at sufficient levels to support outer retinal metabolism.
Type
conference paper
Web of Science ID
WOS:000443968600047
Author(s)
Peachey, Neal S.
Yu, Minzhong
Han, John Y. S.
Pellerin, Luc
Philp, Nancy J.
Date Issued
2018-01-01
Publisher
Publisher place
Cham
Published in
Retinal Degenerative Diseases: Mechanisms And Experimental Therapy
ISBN of the book
978-3-319-75402-4
978-3-319-75401-7
Series title/Series vol.
Advances in Experimental Medicine and Biology; 1074
Start page
375
End page
380
Editorial or Peer reviewed
REVIEWED
Written at
EPFL
EPFL units
| Event name | Event place | Event date |
Kyoto, JAPAN | Sep 19-24, 2016 | |
Available on Infoscience
December 13, 2018
Use this identifier to reference this record