Repository logo

Infoscience

  • English
  • French
Log In
Logo EPFL, École polytechnique fédérale de Lausanne

Infoscience

  • English
  • French
Log In
  1. Home
  2. Academic and Research Output
  3. Journal articles
  4. Synchrotron radiation Imaging of internal structures in live animals
 
research article

Synchrotron radiation Imaging of internal structures in live animals

Lee, K. H.
•
Hwu, Y.
•
Je, J. H.
Show more
2002
Yonsei Medical Journal

Ionizing radiation has long been used in medicine since the discovery of X-rays. Diagnostic imaging using synchrotron radiation has been under investigation since Rubenstein et al. reported dual-energy iodine-K-edge subtraction coronary angiography. Recently, computed tomography (CT) and magnetic resonance imaging (MRI) have provided better quality results than conventional radiology, providing important information on human internal structures. However, such techniques are unable to detect fine micron sized structures for the early diagnosis of tumors, vascular diseases and other medical objectives. Third generation synchrotron X-rays are well known for their superiority in coherence and energy tunability with respect to conventional X-rays. Consequently, new contrast mechanisms with a superior spatial resolution are becoming available. Here we present the extremely fine details of five animal internal structures using unmonochromatized synchrotron X-rays (white beam) and a simple detector system. Natural movements of the internal organs are also shown. The results indicate that this imaging technique can be applied to investigating microstructures and evaluating the function of the internal organs. Furthermore, this imaging system may be applied to humans as the next tool beyond CT and MRI.

  • Details
  • Metrics
Type
research article
Web of Science ID

WOS:000174192200005

Author(s)
Lee, K. H.
Hwu, Y.
Je, J. H.
Tsai, W. L.
Choi, E. W.
Kim, Y. C.
Kim, H. J.
Seong, J. K.
Yi, S. W.
Ryo, H. S.
Show more
Date Issued

2002

Published in
Yonsei Medical Journal
Volume

43

Issue

1

Start page

25

End page

30

Subjects

synchrotron radiation

•

white beam

•

imaging technique

•

phase contrast

•

internal organ

•

X-RAY CT

•

COMPUTED-TOMOGRAPHY

•

CORONARY ANGIOGRAPHY

•

MAMMOGRAPHY

•

MODEL

•

MICROANGIOGRAPHY

•

MICROTOMOGRAPHY

•

ANGIOGENESIS

•

SPECIMEN

•

GROWTH

Note

Acad Sinica, Med Res Ctr, Taipei 11529, Taiwan. Acad Sinica, Inst Phys, Taipei 11529, Taiwan. Pohang Univ Sci & Technol, Dept Mat Sci, Pohang, South Korea. Yonsei Univ, Coll Med, Dept Radiol, Seoul 120749, South Korea. Yonsei Univ, Coll Dent, Dept Periodontol, Seoul 120749, South Korea. Ecole Polytech Fed Lausanne, IPA, CH-1015 Lausanne, Switzerland. Lee, KH, Yonsei Med Res Ctr, CPO Box 8044, Seoul 120752, South Korea.

ISI Document Delivery No.: 527NM

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LSE  
LPRX  
Available on Infoscience
October 3, 2006
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/234882
Logo EPFL, École polytechnique fédérale de Lausanne
  • Contact
  • infoscience@epfl.ch

  • Follow us on Facebook
  • Follow us on Instagram
  • Follow us on LinkedIn
  • Follow us on X
  • Follow us on Youtube
AccessibilityLegal noticePrivacy policyCookie settingsEnd User AgreementGet helpFeedback

Infoscience is a service managed and provided by the Library and IT Services of EPFL. © EPFL, tous droits réservés