Synthesis of a model bicyclic C-O-D-O-E ring of vancomycin by a one-pot, double SNAr based macrocyclization

Zhu, Jieping

doi:10.1039/cc9960001029

research article

Synthesis of a model bicyclic C-O-D-O-E ring of vancomycin by a one-pot, double SNAr based macrocyclization

Beugelmans, Rene

•

Bois-Choussy, Michele

•

Vergne, Caroline

1996

Chemical Communications (ChemComm)

Double cyclization of linear pentapeptide I by treatment with CsF in DMF at -5 Deg gives a model bicyclic (C)-O-(D)-O-(E) ring analog of vancomycin in a one step. [on SciFinder (R)]