System to deliver adaptive epidural and/or subdural electrical spinal cord stimulation to facilitate and restore locomotion after a neuromotor impairment
The present disclosure provides a closed-loop system for real-time control of epidural and/or subdural electrical stimulation comprising means for applying to a subject neuromodulation with adjustable stimulation parameters, said means being operatively connected with a real-time monitoring component comprising sensors continuously acquiring feedback signals from said subject, said signals being neural signals and/or signals providing features of motion of said subject, said system being operatively connected with a signal processing device receiving said feedback signals and operating real-time automatic control algorithms, said signal processing device being operatively connected with said means and providing said means with new stimulation parameters, with minimum delay. The system of the disclosure improves consistency of walking in a subject with a neuromotor impairment. A Real Time Automatic Control Algorithm is used, comprising a feedforward component employing a single input-single output model (SISO), a multiple input-single output (MISO) model, or a multiple input-multiple output (MIMO) model.
61756867
Alternative title(s) : (de) System zur bereitstellung von adaptiver elektrischer rückenmarksstimulation zur ermöglichung und wiederherstellung der bewegung nach einer neuromotorischen störung (fr) Système permettant de distribuer une stimulation de moelle épinière électrique adaptative pour faciliter et restaurer la locomotion après un trouble neuromoteur (en) System to deliver adaptive electrical spinal cord stimulation to facilitate and restore locomotion after a neuromotor impairment
TTO:6.1182.2
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