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Erythrocyte-binding therapeutics

Hubbel, Jeffrey  
•
Kontos, Stephane
•
Dane, Karen
Show more
2013

Peptides that specifically bind erythrocytes are described. These are provided as peptidic ligands having sequences that specifically bind, or as antibodies or fragments thereof that provide specific binding, to erythrocytes. The peptides may be prepared as molecular fusions with therapeutic agents, tolerizing antigens, or targeting peptides. Immunotolerance may be created by use of the fusions and choice of an antigen on a substance for which tolerance is desired. Fusions with targeting peptides direct the fusions to the target, for instance a tumor, where the erythrocyte-binding ligands reduce or entirely eliminate blood flow to the tumor by recruiting erythrocytes to the target.

  • Details
  • Metrics
Type
patent
EPO Family ID

48326347

45564995

46455557

51985354

Author(s)
Hubbel, Jeffrey  
•
Kontos, Stephane
•
Dane, Karen
•
Hubbell, Jeffrey  
Note

Alternative title(s) : (de) Erythrozytenbindende therapeutika (fr) Agents thérapeutiques se liant aux érythrocytes

TTO classification

TTO:6.1008

EPFL units
LMRP  
TTO  
DOICountry codeKind codeDate issued

US11884721

US

B2

2024-01-30

JP2022184955

JP

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2022-12-13

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2022-05-27

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2022-04-28

US11246943

US

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2022-02-15

US2021238277

US

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2021-08-05

CA2807942

CA

C

2021-07-27

AU2019257362

AU

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2021-07-01

US2021079077

US

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2021-03-18

US10919963

US

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2021-02-16

US10800838

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2020-10-13

JP2020147591

JP

A

2020-09-17

ES2781773

ES

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2020-09-07

EA035931

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2020-09-02

JP6716619

JP

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2020-07-01

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2020-05-13

IL234056

IL

B

2020-04-30

US2020101169

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2020-04-02

JP6648184

JP

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2020-02-14

EP2814500

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2020-01-08

US2019382479

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2019-12-19

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2019-11-14

US10471155

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2019-11-12

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HK1256601

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HK

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2019-09-20

US10392437

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2019-08-27

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US10265415

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2019-04-23

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2018-04-12

US9901645

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2018-02-27

US9901646

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2018-02-27

CN103282380

CN

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2018-02-16

US9878048

US

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2018-01-30

AU2017276218

AU

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BR112014020304

BR

A8

2018-01-16

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2017-11-14

EA028087

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2017-10-05

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NZ

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2016-12-29

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2016-12-15

US9518087

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2016-12-13

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2016-11-17

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HK1202051

HK

A1

2015-09-18

MX2014009900

MX

A

2015-06-02

JP2015508770

JP

A

2015-03-23

KR20150010699

KR

A

2015-01-28

CN104271148

CN

A

2015-01-07

EA201491524

EA

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EP2814500

EP

A1

2014-12-24

US2014356384

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A4

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CN103282380

CN

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2013-09-04

CA2864432

CA

A1

2013-08-22

WO2013121296

WO

A1

2013-08-22

EP2603520

EP

A2

2013-06-19

WO2012021512

WO

A8

2013-04-25

AU2011289579

AU

A1

2013-03-21

US2012178139

US

A1

2012-07-12

WO2012021512

WO

A3

2012-06-21

CA2807942

CA

A1

2012-02-16

US2012039989

US

A1

2012-02-16

WO2012021512

WO

A2

2012-02-16

Available on Infoscience
September 22, 2015
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/118497
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