The present invention concerns a system for immunoprecipitation of a protein-DNA complex or for capture of a protein-DNA complex including: - a microfluidic device including a plurality of antibody units, wherein each antibody unit includes at least one microfluidic channel, wherein the at least one microfluidic channel includes at least one surface configured to receive a multi-layered assembly of biochemical species for capturing a target molecule to form a biofunctionalized surface; - at least one inlet for providing at least one sample containing DNA binding proteins to the microfluidic device; and - at least one outlet for providing DNA or eluted DNA for sequencing.