LNGF - Functional Neurogenomics Laboratory
12:21Method for in-vitro monitoring of neuronal disorders and use thereof, EP2591356, 2012.
08:49A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease, in Human Molecular Genetics, vol. 23, num. 11, p. 2995-3007, 2014.
08:02Involvement of autophagy in hypoxic-excitotoxic neuronal death, in Autophagy, vol. 10, num. 5, p. 846-860, 2014.
09:14HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration, in Plos Biology, vol. 11, num. 11, p. e1001717, 2013.
16:41HTT-lowering reverses Huntington's disease immune dysfunction caused by NF kappa B pathway dysregulation, in Brain, vol. 137, p. 819-833, 2014.
16:16HDAC4 Does Not Act as a Protein Deacetylase in the Postnatal Murine Brain In Vivo, in Plos One, vol. 8, num. 11, 2013.
08:50Fused 3-Hydroxy-3-trifluoromethylpyrazoles Inhibit Mutant Huntingtin Toxicity, in Acs Medicinal Chemistry Letters, vol. 4, num. 10, p. 979-984, 2013.
10:49Comparative analyses of Purkinje cell gene expression profiles reveal shared molecular abnormalities in models of different polyglutamine diseases, in Brain Research, vol. 1481, p. 37-48, 2012.
16:19An Adeno-Associated Virus-Based Intracellular Sensor of Pathological Nuclear Factor-kappa B Activation for Disease-Inducible Gene Transfer, in Plos One, vol. 8, num. 1, 2013.
09:33MicroRNA-22 (miR-22) Overexpression Is Neuroprotective via General Anti-Apoptotic Effects and May also Target Specific Huntington's Disease-Related Mechanisms, in Plos One, vol. 8, num. 1, 2013.