Microfluidic Large-Scale Integration

• Published in: Science, vol. 298, num. 5593, p. 580-584
• Publication date: 2002

We developed high-density microfluidic chips that contain plumbing networks with thousands of micromechanical valves and hundreds of individually addressable chambers. These fluidic devices are analogous to electronic integrated circuits fabricated using large-scale integration. A key component of these networks is the fluidic multiplexor, which is a combinatorial array of binary valve patterns that exponentially increases the processing power of a network by allowing complex fluid manipulations with a minimal number of inputs. We used these integrated microfluidic networks to construct the microfluidic analog of a comparator array and a microfluidic memory storage device whose behavior resembles random-access memory.

Reference

• LBNC-ARTICLE-2008-001
• doi:10.1126/science.1076996

Record created on 2008-02-15, modified on 2012-03-21